I am going to cheat here and say Peter Cushing.
Cushing starred in Doctor Who and the Daleks, a 1965 movie based loosely o the second Doctor Who serial “The Daleks.” Cushing is essentially playing the First Doctor for the big screen, so the story is not officially canon. Nor I it any good, but that is another matter.
Aside of his brief stint as the Doctor, Cushing has played all sorts of memorable roles. I am a big fan of Hammer Horror films, for which he was a regular player, but Cushing has also done everything from star with the Marx Brothers in A Chump at Oxford, to portray Sherlock Holmes, and oder Darth Vader around as Grand Moff Tarkin.
You cannot beat a career like that.